Article
[Polymorphism of XRCC1 and chromosome damage in workers occupationally exposed to benzene].
Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases - 1 Jun 2012
Zhang Jing, Lü Jian-ping, Zhang Chen, Zhou Li-fang, Ye Yun-jie, Sun Pin, Cheng Zhou-xiang, Xia Zhao-lin
Abstract excerpt
OBJECTIVE: To explore the relationship between the polymorphisms of DNA repair gene (XRCC1 194, 280 and 399) and the chromosomal damage induced by benzene. METHODS: The chromosomal damage of the peripheral lymphocytes in 459 workers occupationally exposed to benzene and 88 non-exposed controls were detected with cytokinesis-block micronucleus (CBMN) assay. PCR-RFLP technique was used to measure polymorphisms in...
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