Article
Cancer susceptibility syndromes in children in the area of broad clinical use of massive parallel sequencing.
European journal of pediatrics - 1 Aug 2015
Kuhlen Michaela, Borkhardt Arndt
Abstract excerpt
UNLABELLED: Children diagnosed with cancer are considered for inherited cancer susceptibility testing according to well-established clinical criteria. With increasing efforts to personalize cancer medicine, comprehensive genome analyses will find its way into daily clinical routine in pediatric oncology. Whole genome and exome sequencing unavoidably generates incidental findings. The somatic "molecular make-up"...
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