Article

Cancer Predisposition Syndromes in Children: Who, How and When Should Genetic Studies Be Considered?

2024-03-13

Abstract excerpt

Early detection of cancer predisposition syndromes (CPS) is crucial to determine optimal treatments and follow-up, and to provide appropriate genetic counseling. This study outlines an approach in a pediatric oncology unit, where 50 randomly selected patients underwent clinical assessment, leading to 44 eligible for genetic testing. We identified 3 pathogenic or likely pathogenic variants in genes associated with...

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Literature Corpus work: 89fb70ff-769d-5f7d-b962-943453bf9313
DOI: 10.22541/au.171030988.86378176/v1

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