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Genomic Newborn Screening for Pediatric Cancer Predisposition Syndromes: A Holistic Approach

26 May 2024

Abstract excerpt

As next-generation sequencing (NGS) has become more widely used, germline and rare genetic variations responsible for inherited illnesses, including cancer predisposition syndromes (CPSs) that account for up to 10% of childhood malignancies, have been found. The CPSs are a group of germline genetic disorders that have been identified as risk factors for pediatric cancer development. Excluding a few "classic"...

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PMID: 38893137
DOI: 10.3390/cancers16112017

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