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Article

iPSCs as a major opportunity to understand and cure age-related diseases.

Biogerontology - 1 Aug 2015

Lemey Camille, Milhavet Ollivier, Lemaitre Jean-Marc

Abstract excerpt

Cellular senescence plays an important role in the process of aging and is often associated with age-related diseases. Senescence was originally considered as a barrier to cell reprogramming, however we developed a strategy to overcome this hurdle and derive induced pluripotent stem cells (iPSCs) from senescent cells and cells from centenarians. Furthermore we showed that the newly generated iPSCs could be...

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Identifiers

PMID: 25981448
DOI: 10.1007/s10522-015-9579-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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