Article
[MyD88 L265P mutation and B cell tumor].
Zhongguo shi yan xue ye xue za zhi - 1 Feb 2014
Chen Hai-Min, Hou Jian
Abstract excerpt
Myeloid differentiation factor (MyD88) is an important adaptor protein mediating the signal transduction of most Toll-like receptors (TLR), interleukin-1 receptor (IL-1R) and interleukin-18 receptor (IL-18R) that play a key role to mediate innate immune response. Recently, activating of MYD88 L265 mutation has been reported in about of 90% lymphoplasmacytoid lymphoma/Waldenström's Macroglobulinemia, about of 29%...
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