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Article

Microevolution of Virulence-Related Genes in Helicobacter pylori Familial Infection

15 May 2015

Abstract excerpt

Helicobacter pylori, a bacterial pathogen that can infect human stomach causing gastritis, ulcers and cancer, is known to have a high degree of genome/epigenome diversity as the result of mutation and recombination. The bacteria often infect in childhood and persist for the life of the host. One of the reasons of the rapid evolution of H. pylori is that it changes its genome drastically for adaptation to a new...

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PMID: 25978460
DOI: 10.1371/journal.pone.0127197

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