Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

FAS and FASLG genetic variants and risk for second primary malignancy in patients with squamous cell carcinoma of the head and neck.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jun 2010

Lei Dapeng, Sturgis Erich M, Wang Li-E, Liu Zhensheng, Zafereo Mark E, Wei Qingyi, Li Guojun

Abstract excerpt

BACKGROUND: Single-nucleotide polymorphisms in the promoter region of the FAS and FASLG may alter the transcriptional activity of these genes. We therefore investigated the association between the FAS and FASLG polymorphisms and risk for second primary malignancy (SPM) after index squamous cell carcinoma of the head and neck (SCCHN). METHODS: We used log-rank test and Cox proportional hazard models to assess the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Carcinoma, Squamous Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease Progression

Share to Fas Ligand Protein

Share to fas Receptor

Share to Head and Neck Neoplasms

Share to Neoplasms, Second Primary

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 20501759
DOI: 10.1158/1055-9965.EPI-10-0030
PMCID: PMC2883025

Genes

FAS
FASLG
IMPACT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

FAS and FASLG genetic variants and risk for second primary malignancy in patients with squamous cell carcinoma of the head and neck.PMID 20501759Read ↗

Polymorphisms of FAS and FAS ligand genes involved in the death pathway and risk and progression of squamous cell carcinoma of the head and neck.Semantic proximity Read ↗

p73 G4C14-to-A4T14 polymorphism and risk of second primary malignancy after index squamous cell carcinoma of head and neck.Semantic proximity Read ↗

Genetic variants in p53-related genes confer susceptibility to second primary malignancy in patients with index squamous cell carcinoma of head and neck.Semantic proximity Read ↗

Single nucleotide polymorphisms and the risk of developing a second primary cancer among head and neck cancer patients: a systematic literature review and meta-analysis.Semantic proximity Read ↗

Apoptotic variants as predictors of risk of oropharyngeal cancer recurrence after definitive radiotherapy.Semantic proximity Read ↗

Differential cancer risk and survival in Indian oral cancer patients with genic region FAS and FASL polymorphisms.Semantic proximity Read ↗

Quantitative assessment of the relationship between Fas/FasL genes polymorphisms and head and neck cancer risk.Semantic proximity Read ↗

Genetic polymorphisms of p21 and risk of second primary malignancy in patients with index squamous cell carcinoma of the head and neck.Semantic proximity Read ↗

Polymorphisms of death pathway genes FAS and FASL and risk of nasopharyngeal carcinoma.Semantic proximity Read ↗

Polymorphisms of death pathway genes FAS and FASL in esophageal squamous-cell carcinoma.Semantic proximity Read ↗

p14ARF genetic polymorphisms and susceptibility to second primary malignancy in patients with index squamous cell carcinoma of the head and neck.Semantic proximity Read ↗

Nucleotide excision repair core gene polymorphisms and risk of second primary malignancy in patients with index squamous cell carcinoma of the head and neck.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.