Article
The Shepherds' Tale: A Genome-Wide Study across 9 Dog Breeds Implicates Two Loci in the Regulation of Fructosamine Serum Concentration in Belgian Shepherds.
PloS one - 1 Jan 2015
Forsberg Simon K G, Kierczak Marcin, Ljungvall Ingrid, Merveille Anne-Christine, Gouni Vassiliki, Wiberg Maria, Lundgren Willesen Jakob, Hanås Sofia, Lequarré Anne-Sophie, Mejer Sørensen Louise, Tiret Laurent, McEntee Kathleen, Seppälä Eija, Koch Jørgen, Battaille Géraldine, Lohi Hannes, Fredholm Merete, Chetboul Valerie, Häggström Jens, Carlborg Örjan, Lindblad-Toh Kerstin, Höglund Katja
Abstract excerpt
Diabetes mellitus is a serious health problem in both dogs and humans. Certain dog breeds show high prevalence of the disease, whereas other breeds are at low risk. Fructosamine and glycated haemoglobin (HbA1c) are two major biomarkers of glycaemia, where serum concentrations reflect glucose turnover over the past few weeks to months. In this study, we searched for genetic factors influencing variation in serum...
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