Article
Heterospecific SNP diversity in humans and rhesus macaque (Macaca mulatta).
Journal of medical primatology - 1 Aug 2015
Ng Jillian, Trask Jessica Satkoski, Smith David Glenn, Kanthaswamy Sree
Abstract excerpt
BACKGROUND: Conservation of single nucleotide polymorphisms (SNPs) between human and other primates (i.e., heterospecific SNPs) in candidate genes can be used to assess the utility of those organisms as models for human biomedical research. METHODS: A total of 59,691 heterospecific SNPs in 22 rhesus macaques and 20 humans were analyzed for human trait associations and 4207 heterospecific SNPs biallelic in both...
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