Article
ARID1A and TERT promoter mutations in dedifferentiated meningioma.
Cancer genetics - 1 Jun 2015
Abedalthagafi Malak S, Bi Wenya Linda, Merrill Parker H, Gibson William J, Rose Matthew F, Du Ziming, Francis Joshua M, Du Rose, Dunn Ian F, Ligon Azra H, Beroukhim Rameen, Santagata Sandro
Abstract excerpt
Unlike patients with World Health Organization (WHO) grade I meningiomas, which are considered benign, patients with WHO grade III meningiomas have very high mortality rates. The principles underlying tumor progression in meningioma are largely unknown, yet a detailed understanding of these mechanisms will be required for effective management of patients with these high grade lethal tumors. We present a case of...
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