Article
LRRK2 mutations in Parkinson disease; a sex effect or lack thereof? A meta-analysis.
Parkinsonism & related disorders - 1 Jul 2015
Gan-Or Ziv, Leblond Claire S, Mallett Victoria, Orr-Urtreger Avi, Dion Patrick A, Rouleau Guy A
Abstract excerpt
BACKGROUND: It is currently under debate whether there is a sex effect in LRRK2-associated Parkinson disease (PD), as several studies suggested such effect while others did not. METHODS: All case-control studies describing LRRK2 mutations and PD were examined, and papers with data on sex and LRRK2 mutations in both patients and controls were included (n = 17) in a sex-stratified meta-analysis. Additional studies...
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