Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

2'-Hydroxyflavanone: A promising molecule for kidney cancer prevention.

Biochemical pharmacology - 1 Aug 2015

Singhal Sharad S, Singhal Jyotsana, Figarola James L, Riggs Arthur, Horne David, Awasthi Sanjay

Abstract excerpt

Kidney cancer, also known as renal cell carcinoma (RCC), is one of the top 10 diagnosed cancers in the USA, and the incidence is rising. Despite major improvements in drug therapy strategies, RCC remains a deadly malignancy if not found and removed in its early stages. RCC is so highly drug-resistant that no effective life-prolonging regimen of cytotoxic chemotherapy has been demonstrated for RCC, despite several...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antineoplastic Agents, Phytogenic
Share to Carcinogens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Renal Cell

Share to Drug Resistance, Neoplasm

Share to Flavanones

Share to Gene Expression Regulation, Neoplastic

Share to Kidney Neoplasms

Share to Von Hippel-Lindau Tumor Suppressor Protein

Source

Identifiers

PMID: 25957660
DOI: 10.1016/j.bcp.2015.04.022

Genes

VHL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

2'-Hydroxyflavanone: A promising molecule for kidney cancer prevention.PMID 25957660Read ↗

2'-hydroxyflavanone inhibits proliferation, tumor vascularization and promotes normal differentiation in VHL-mutant renal cell carcinoma.Semantic proximity Read ↗

Plant‐Derived Agents for Counteracting Cisplatin‐Induced NephrotoxicitySemantic proximity Read ↗

Aristolochic Acid-Induced Nephrotoxicity: Molecular Mechanisms and Potential Protective ApproachesSemantic proximity Read ↗

Screening DNA Damage in the Rat Kidney and Liver by Untargeted DNA AdductomicsSemantic proximity Read ↗

Treatment of kidney cancerSemantic proximity Read ↗

Coumarins as Potential Inhibitors of DNA Polymerases and Reverse Transcriptases. Searching New Antiretroviral and Antitumoral DrugsSemantic proximity Read ↗

Unveiling the Potential of Watermelon Rind Extract: Impact on Cell Proliferation, Apoptosis, Senescence, and Transcriptomic Profile in Human Renal Adenocarcinoma CellsSemantic proximity Read ↗

A Molecule Targeting VHL-Deficient Renal Cell Carcinoma that Induces AutophagySemantic proximity Read ↗

From Fruit Waste to Medical Insight: The Comprehensive Role of Watermelon Rind Extract on Renal Adenocarcinoma Cellular and Transcriptomic DynamicsSemantic proximity Read ↗

Next Generation Antineoplastic Agents: A Review on Structurally Modified Vinblastine (VBL) AnaloguesSemantic proximity Read ↗

Aristolochic acid-induced genotoxicity and toxicogenomic changes in rodentsSemantic proximity Read ↗

Identification of the Lipodepsipeptide MDN-0066, a Novel Inhibitor of VHL/HIF Pathway Produced by a New Pseudomonas SpeciesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.