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Article

Mutations in Nature Conferred a High Affinity Phosphatidylinositol 4,5-Bisphosphate-binding Site in Vertebrate Inwardly Rectifying Potassium Channels.

The Journal of biological chemistry - 3 Jul 2015

Tang Qiong-Yao, Larry Trevor, Hendra Kalen, Yamamoto Erica, Bell Jessica, Cui Meng, Logothetis Diomedes E, Boland Linda M

Abstract excerpt

All vertebrate inwardly rectifying potassium (Kir) channels are activated by phosphatidylinositol 4,5-bisphosphate (PIP2) (Logothetis, D. E., Petrou, V. I., Zhang, M., Mahajan, R., Meng, X. Y., Adney, S. K., Cui, M., and Baki, L. (2015) Annu. Rev. Physiol. 77, 81-104; Fürst, O., Mondou, B., and D...

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Identifiers

PMID: 25957411
DOI: 10.1074/jbc.M115.640409
PMCID: PMC4505406

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25957411-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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