Article
Practical problems with clinical guidelines for breast cancer prevention based on remaining lifetime risk.
Journal of the National Cancer Institute - 1 Jul 2015
Quante Anne S, Whittemore Alice S, Shriver Tom, Hopper John L, Strauch Konstantin, Terry Mary Beth
Abstract excerpt
BACKGROUND: Clinical guidelines for breast cancer chemoprevention and MRI screening involve estimates of remaining lifetime risk (RLR); in the United States, women with an RLR of 20% or higher meet "high-risk" criteria for MRI screening. METHODS: We prospectively followed 1764 women without breast cancer to compare the RLRs and 10-year risks assigned by the risk models International Breast Cancer Intervention...
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