Article
Vemurafenib in BRAFV600 mutated metastatic melanoma: a subanalysis of the Italian population of a global safety study.
Future oncology (London, England) - 1 Jan 2015
Del Vecchio Michele, Ascierto Paolo Antonio, Mandalà Mario, Sileni Vanna Chiarion, Maio Michele, Di Guardo Lorenza, Simeone Ester, Queirolo Paola
Abstract excerpt
AIM: We describe the ad interim analysis of the Italian cohort of the global safety study on vemurafenib in patients with metastatic melanoma. PATIENTS & METHODS: A total of 385 patients received vemurafenib 960 mg twice daily. RESULTS: In total, 330 patients (86%) reported adverse events; 16 serious adverse events were observed (three related to vemurafenib). The response rate was 30.4%. Median progression-free...
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