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Creation of a Human Secretome: A Novel Composite Library of Human Secreted Proteins: Validation Using Ovarian Cancer Gene Expression Data and a Virtual Secretome Array

5 May 2015

Abstract excerpt

PURPOSE: To generate a comprehensive "Secretome" of proteins potentially found in the blood and derive a virtual Affymetrix array. To validate the utility of this database for the discovery of novel serum-based biomarkers using ovarian cancer transcriptomic data. EXPERIMENTAL DESIGN: The secretome was constructed by aggregating the data from databases of known secreted proteins, transmembrane or membrane...

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PMID: 25944803
DOI: 10.1158/1078-0432.ccr-14-3173

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