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Seromic profiling of ovarian and pancreatic cancer

1 Mar 2010

Abstract excerpt

Autoantibodies, a hallmark of both autoimmunity and cancer, represent an easily accessible surrogate for measuring adaptive immune responses to cancer. Sera can now be assayed for reactivity against thousands of proteins using microarrays, but there is no agreed-upon standard to analyze results. We developed a set of tailored quality control and normalization procedures based on ELISA validation to allow patient...

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PMID: 20194765
DOI: 10.1073/pnas.0914213107

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