Article
The cyclin-A CYCA1;2/TAM is required for the meiosis I to meiosis II transition and cooperates with OSD1 for the prophase to first meiotic division transition.
PLoS genetics - 17 Jun 2010
d'Erfurth Isabelle, Cromer Laurence, Jolivet Sylvie, Girard Chloé, Horlow Christine, Sun Yujin, To Jennifer P C, Berchowitz Luke E, Copenhaver Gregory P, Mercier Raphael
Abstract excerpt
Meiosis halves the chromosome number because its two divisions follow a single round of DNA replication. This process involves two cell transitions, the transition from prophase to the first meiotic division (meiosis I) and the unique meiosis I to meiosis II transition. We show here that the A-type cyclin CYCA1;2/TAM plays a major role in both transitions in Arabidopsis. A series of tam mutants failed to enter...
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