Article
The CDK inhibitor NtKIS1a is involved in plant development, endoreduplication and restores normal development of cyclin D3; 1-overexpressing plants.
Journal of cell science - 1 Mar 2002
Jasinski Sophie, Riou-Khamlichi Catherine, Roche Odile, Perennes Claudette, Bergounioux Catherine, Glab Nathalie
Abstract excerpt
Plant development requires stringent controls between cell proliferation and cell differentiation. Proliferation is positively regulated by cyclin dependent kinases (CDKs). Acting in opposition to CDKs are CDK inhibitors (CKIs). The first tobacco CKI (NtKIS1a) identified was shown to inhibit in vitro the kinase activity of CDK/cyclin complexes and to interact with CDK and D-cyclins. However, these features, which...
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