Article
Tn-seq explorer: a tool for analysis of high-throughput sequencing data of transposon mutant libraries.
PloS one - 1 Jan 2015
Solaimanpour Sina, Sarmiento Felipe, Mrázek Jan
Abstract excerpt
Tn-seq is a high throughput technique for analysis of transposon mutant libraries. Tn-seq Explorer was developed as a convenient and easy-to-use package of tools for exploration of the Tn-seq data. In a typical application, the user will have obtained a collection of sequence reads adjacent to transposon insertions in a reference genome. The reads are first aligned to the reference genome using one of the tools...
Topics
- Bacteria
- Computational Biology
- DNA Transposable Elements
- Databases, Nucleic Acid
- Gene Library
- Genomics
- High-Throughput Nucleotide Sequencing
- Mutation
- Software
