Article
Differential effects of BDNF val(66)met in repetitive associative learning paradigms.
Neurobiology of learning and memory - 1 Sept 2015
Freundlieb Nils, Backhaus Winifried, Brüggemann Norbert, Gerloff Christian, Klein Christine, Pinnschmidt Hans O, Hummel Friedhelm C
Abstract excerpt
In healthy young subjects, the brain derived neurotropic factor (BDNF) val(66)met polymorphism negatively affects behavioural outcome in short-term motor cortex or hippocampus-based learning paradigms. In repetitive training paradigms over several days this effect can be overcome, in tests involving other brain areas even positive effects were found. To further specify the role of this polymorphism in cognitive...
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