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Article

Brain-derived neurotrophic factor genetic polymorphism rs6265 and creativity.

PloS one - 1 Jan 2023

Hertenstein Elisabeth, Kuhn Marion, Landmann Nina, Maier Jonathan-Gabriel, Schneider Carlotta Louisa, Fehér Kristoffer Daniel, Frase Lukas, Riemann Dieter, Feige Bernd, Nissen Christoph

Abstract excerpt

The protein brain-derived neurotrophic factor (BDNF) promotes neural plasticity of the central nervous system and plays an important role for learning and memory. A single nucleotide polymorphism (rs6265) at position 66 in the pro-region of the human BDNF gene, resulting in a substitution of the amino acid valine (val) with methionine (met), leads to attenuated BDNF secretion and has been associated with reduced...

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PMID: 37703265
DOI: 10.1371/journal.pone.0291397
PMCID: PMC10499242

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