Article
Human renal carcinoma cells respond to Newcastle disease virus infection through activation of the p38 MAPK/NF-κB/IκBα pathway.
Cellular oncology (Dordrecht, Netherlands) - 1 Aug 2015
Ch'ng Wei-Choong, Abd-Aziz Noraini, Ong Meng-Hua, Stanbridge Eric J, Shafee Norazizah
Abstract excerpt
PURPOSE: Newcastle disease virus (NDV) is an oncolytic virus that is known to have a higher preference to cancer cells than to normal cells. It has been proposed that this higher preference may be due to defects in the interferon (IFN) responses of cancer cells. The exact mechanism underlying thi...
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