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The matrix (M) protein of newcastle disease virus binds to human bax through its BH3 domain

3 Aug 2011

Abstract excerpt

The underlying mechanisms by which Newcastle disease virus (NDV) kills cancer cells are still unclear. Recent discoveries have shown that many viruses contain Bcl-2 homology-like domains which enabled their interaction with Bcl-2 family members, and thereby accounting for their virulence and pathogenicity. Alignment of the protein sequences of Malaysian strain of NDV, known as AF2240, with those from members of...

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PMID: 21810274
DOI: 10.1186/1743-422x-8-385

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