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Article

The key pathways and genes related to oncolytic Newcastle disease virus-induced phenotypic changes in ovarian cancer cells.

Journal of microbiology (Seoul, Korea) - 1 Apr 2025

Song Wei, Yuan Yuan, Cao Fangfang, Pan Huazheng, Liu Yaqing

Abstract excerpt

The poor prognosis and high recurrence rate of ovarian cancer highlight the urgent need to develop new therapeutic strategies. Oncolytic Newcastle disease virus (NDV) can kill cancer cells directly and regulate innate and adaptive immunity. In this study, ovarian cancer cells infected with or without velogenic NDV-BJ were subjected to a CCK-8 assay for detecting cell proliferation, flow cytometry for detecting...

Read the complete abstract on PubMed

Topics

Humans
Newcastle disease virus
Female
Ovarian Neoplasms
Cell Line, Tumor
Oncolytic Viruses

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Cell Proliferation

Apoptosis

Oncolytic Virotherapy

Signal Transduction

Cell Movement

Phenotype

Gene Expression Profiling

Cell Cycle

Gene Expression Regulation, Neoplastic

Source

Open in PubMed Open full text

Identifiers

PMID: 40313149
DOI: 10.71150/jm.2411018
PMCID: PMC13577072

Genes

CCK
GADD45B
RELA
SESN2

Provenance

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