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Article

The Differential Effects of Anti-Diabetic Thiazolidinedione on Prostate Cancer Progression Are Linked to the TR4 Nuclear Receptor Expression Status.

Neoplasia (New York, N.Y.) - 1 Apr 2015

Lin Shin-Jen, Lin Chang-Yi, Yang Dong-Rong, Izumi Kouji, Yan Emily, Niu Xiaodan, Chang Hong-Chiang, Miyamoto Hiroshi, Wang Nancy, Li Gonghui, Chang Chawnshang

Abstract excerpt

The insulin sensitizers, thiazolidinediones (TZDs), have been used as anti-diabetic drugs since the discovery of their ability to alter insulin resistance through transactivation of peroxisome proliferator-activated receptors (PPARs). However, their side effects in hepatitis, cardiovascular disea...

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Identifiers

PMID: 25925376
DOI: 10.1016/j.neo.2015.02.005
PMCID: PMC4415117

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HRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25925376-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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