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Article

Private mitochondrial DNA variants in danish patients with hypertrophic cardiomyopathy.

PloS one - 1 Jan 2015

Hagen Christian M, Aidt Frederik H, Havndrup Ole, Hedley Paula L, Jensen Morten K, Kanters Jørgen K, Pham Tam T, Bundgaard Henning, Christiansen Michael

Abstract excerpt

Hypertrophic cardiomyopathy (HCM) is a genetic cardiac disease primarily caused by mutations in genes coding for sarcomeric proteins. A molecular-genetic etiology can be established in ~60% of cases. Evolutionarily conserved mitochondrial DNA (mtDNA) haplogroups are susceptibility factors for HCM. Several polymorphic mtDNA variants are associated with a variety of late-onset degenerative diseases and affect...

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Share to Cardiomyopathy, Hypertrophic
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Mitochondrial

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Share to Polymorphism, Single Nucleotide

Source

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Identifiers

PMID: 25923817
DOI: 10.1371/journal.pone.0124540
PMCID: PMC4414448

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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