Article
Whole mitochondrial genome sequencing of Malaysian patients with cardiomyopathy.
PeerJ - 1 Jan 2022
Kuan Sheh Wen, Chua Kek Heng, Tan E-Wei, Tan Lay Koon, Loch Alexander, Kee Boon Pin
Abstract excerpt
Cardiomyopathy (CMP) constitutes a diverse group of myocardium diseases affecting the pumping ability of the heart. Genetic predisposition is among the major factors affecting the development of CMP. Globally, there are over 100 genes in autosomal and mitochondrial DNA (mtDNA) that have been reported to be associated with the pathogenesis of CMP. However, most of the genetic studies have been conducted in Western...
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