Article
Expression Profile Analysis of Zinc Transporters (ZIP4, ZIP9, ZIP11, ZnT9) in Gliomas and their Correlation with IDH1 Mutation Status.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2015
Kang Xing, Chen Rong, Zhang Jie, Li Gang, Dai Peng-Gao, Chen Chao, Wang Hui-Juan
Abstract excerpt
BACKGROUND: Zinc transporters have been considered as essential regulators in many cancers; however, their mechanisms remain unknown, especially in gliomas. Isocitrate dehydrogenase 1(IDH1) mutation is crucial to glioma. This study aimed to investigate whether zinc transporters are correlated with glioma grade and IDH1 mutation status. MATERIALS AND METHODS: IDH1 mutation status and mRNA expression of four zinc...
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