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Article

The application of single strand conformation polymorphism (SSCP) analysis in determining Hepatitis E virus intra-host diversity.

Journal of virological methods - 1 Sept 2015

Černi S, Prpić J, Jemeršić L, Škorić D

Abstract excerpt

Genetic heterogeneity of RNA populations influences virus pathogenesis, epidemiology and evolution. Therefore, accurate information regarding virus genetic structure is highly important for both diagnostic and scientific purposes. For the Hepatitis E virus (HEV), the causal agent of hepatitis in humans, the intra-host population structure has been poorly investigated, mainly using the less sensitive RFLP-based...

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PMID: 25920567
DOI: 10.1016/j.jviromet.2015.04.020

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