Article
Role of heteroplasmic mutations in the mitochondrial genome and the ID4 gene promoter methylation region in the pathogenesis of chronic aplastic anemia in patients suffering from Kidney yin deficiency.
Chinese journal of integrative medicine - 1 Jun 2016
Cui Xing, Wang Jing-Yi, Liu Kui, Cui Si-Yuan, Zhang Jie, Luo Ya-Qin, Wang Xin
Abstract excerpt
OBJECTIVE: To analyze changes in gene amplification in the mitochondrial genome and in the ID4 gene promoter methylation region in patients with chronic aplastic anemia (CAA) suffering from Kidney (Shen) yin deficiency or Kidney yang deficiency. METHODS: Bone marrow and oral epithelium samples were collected from CAA patients with Kidney yin deficiency or Kidney yang deficiency (20 cases). Bone marrow samples...
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