A genome wide association study links glutamate receptor pathway to sporadic Creutzfeldt-Jakob disease risk.

doi:10.1371/journal.pone.0123654

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Article

A genome wide association study links glutamate receptor pathway to sporadic Creutzfeldt-Jakob disease risk.

PloS one - 1 Jan 2014

Sanchez-Juan Pascual, Bishop Matthew T, Kovacs Gabor G, Calero Miguel, Aulchenko Yurii S, Ladogana Anna, Boyd Alison, Lewis Victoria, Ponto Claudia, Calero Olga, Poleggi Anna, Carracedo Ángel, van der Lee Sven J, Ströbel Thomas, Rivadeneira Fernando, Hofman Albert, Haïk Stéphane, Combarros Onofre, Berciano José, Uitterlinden Andre G, Collins Steven J, Budka Herbert, Brandel Jean-Philippe, Laplanche Jean Louis, Pocchiari Maurizio, Zerr Inga, Knight Richard S G, Will Robert G, van Duijn Cornelia M

Abstract excerpt

We performed a genome-wide association (GWA) study in 434 sporadic Creutzfeldt-Jakob disease (sCJD) patients and 1939 controls from the United Kingdom, Germany and The Netherlands. The findings were replicated in an independent sample of 1109 sCJD and 2264 controls provided by a multinational con...

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PMID: 25918841
DOI: 10.1371/journal.pone.0123654
PMCID: PMC4412535

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GRM8
PRNP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25918841-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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