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Article

Integrative Analysis of CRISPR/Cas9 Target Sites in the Human HBB Gene.

BioMed research international - 1 Jan 2015

Luo Yumei, Zhu Detu, Zhang Zhizhuo, Chen Yaoyong, Sun Xiaofang

Abstract excerpt

Recently, the clustered regularly interspaced short palindromic repeats (CRISPR) system has emerged as a powerful customizable artificial nuclease to facilitate precise genetic correction for tissue regeneration and isogenic disease modeling. However, previous studies reported substantial off-target activities of CRISPR system in human cells, and the enormous putative off-target sites are labor-intensive to be...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25918715
DOI: 10.1155/2015/514709
PMCID: PMC4396065

Genes

HBB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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