Article
The association between lower educational attainment and depression owing to shared genetic effects? Results in ~25,000 subjects.
Molecular psychiatry - 1 Jun 2015
Peyrot W J, Lee S H, Milaneschi Y, Abdellaoui A, Byrne E M, Esko T, de Geus E J C, Hemani G, Hottenga J J, Kloiber S, Levinson D F, Lucae S, Martin N G, Medland S E, Metspalu A, Milani L, Noethen M M, Potash J B, Rietschel M, Rietveld C A, Ripke S, Shi J, Willemsen G, Zhu Z, Boomsma D I, Wray N R, Penninx B W J H
Abstract excerpt
An association between lower educational attainment (EA) and an increased risk for depression has been confirmed in various western countries. This study examines whether pleiotropic genetic effects contribute to this association. Therefore, data were analyzed from a total of 9662 major depressive disorder (MDD) cases and 14,949 controls (with no lifetime MDD diagnosis) from the Psychiatric Genomics Consortium...
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