Article
A rare variant in MCF2L identified using exclusion linkage in a pedigree with premature atherosclerosis.
European journal of human genetics : EJHG - 1 Jan 2016
Maiwald Stephanie, Motazacker Mahdi M, van Capelleveen Julian C, Sivapalaratnam Suthesh, van der Wal Allard C, van der Loos Chris, Kastelein John J P, Ouwehand Willem H, Hovingh G Kees, Trip Mieke D, van Buul Jaap D, Dallinga-Thie Geesje M
Abstract excerpt
Cardiovascular disease (CVD) is a major cause of death in Western societies. CVD risk is largely genetically determined. The molecular pathology is, however, not elucidated in a large number of families suffering from CVD. We applied exclusion linkage analysis and next-generation sequencing to el...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.