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Article

Low ambient temperature during early postnatal development fails to cause a permanent induction of brown adipocytes.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Aug 2015

Chabowska-Kita Agnieszka, Trabczynska Anna, Korytko Agnieszka, Kaczmarek Monika M, Kozak Leslie P

Abstract excerpt

The brown adipocyte phenotype (BAP) in white adipose tissue (WAT) is transiently induced in adult mammals in response to reduced ambient temperature. Since it is unknown whether a cold challenge can permanently induce brown adipocytes (BAs), we reared C57BL/6J (B6) and AxB8/PgJ (AxB8) mice at 17 or 29°C from birth to weaning, to assess the BAP in young and adult mice. Energy balance measurements showed that 17°C...

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Identifiers

PMID: 25896784
DOI: 10.1096/fj.15-271395
PMCID: PMC4511198

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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