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Article

Comparison of Twin and Extended Pedigree Designs for Obtaining Heritability Estimates.

Behavior genetics - 1 Jul 2015

Docherty Anna R, Kremen William S, Panizzon Matthew S, Prom-Wormley Elizabeth C, Franz Carol E, Lyons Michael J, Eaves Lindon J, Neale Michael C

Abstract excerpt

This study explores power assumptions relating to extended pedigree designs (EPD) and classical twin designs (CTD). We conducted statistical analyses to compare the power of the two designs for examining neuroimaging phenotypes, varying heritability and varying whether shared environmental variance is fixed or free. Results indicated that CTDs have more power to estimate heritability, with the exception of one...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25894926
DOI: 10.1007/s10519-015-9720-z
PMCID: PMC4459911

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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