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Humanin protects against chemotherapy-induced stage-specific male germ cell apoptosis in rats

16 Apr 2015

Abstract excerpt

Humanin (HN) has cytoprotective action on male germ cells after testicular stress induced by heat and hormonal deprivation. To examine whether HN has protective effects on chemotherapy-induced male germ cell apoptosis, we treated four groups of adult rats with (i) vehicle (control), (ii) HN, (iii) cyclophosphamide (CP); or (iv) HN+CP. To investigate whether the protective effects of HN on germ cells require the...

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PMID: 25891800
DOI: 10.1111/andr.12036

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