Article
Cardiac Mechanical Alterations and Genotype Specific Differences in Subjects With Long QT Syndrome.
JACC. Cardiovascular imaging - 1 May 2015
Leren Ida S, Hasselberg Nina E, Saberniak Jørg, Håland Trine F, Kongsgård Erik, Smiseth Otto A, Edvardsen Thor, Haugaa Kristina H
Abstract excerpt
OBJECTIVES: This study aimed to explore systolic and diastolic function and to investigate genotype-specific differences in subjects with long QT syndrome (LQTS). BACKGROUND: LQTS is an arrhythmogenic cardiac ion channelopathy that traditionally has been considered a purely electrical disease. The most commonly affected ion channels are the slow potassium channel, IKs (KCNQ1 gene/LQT1), and the rapid potassium...
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