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Article

Transmural differences in myocardial contraction in long-QT syndrome: mechanical consequences of ion channel dysfunction.

Circulation - 5 Oct 2010

Haugaa Kristina Hermann, Amlie Jan P, Berge Knut Erik, Leren Trond P, Smiseth Otto A, Edvardsen Thor

Abstract excerpt

BACKGROUND: Long-QT syndrome (LQTS) is characterized by prolonged myocardial action potential duration. The longest action potential duration is reported in the endomyocardium and midmyocardium. Prolonged action potential duration in LQTS may cause prolonged cardiac contraction, which can be assessed by strain echocardiography. We hypothesized that myocardial contraction is most prolonged in subendocardial...

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Source

Identifiers

PMID: 20855658
DOI: 10.1161/CIRCULATIONAHA.110.960377

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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