Article
Genetic variants in AKR1B10 associate with human eating behavior.
BMC genetics - 25 Mar 2015
Rohde Kerstin, Federbusch Martin, Horstmann Annette, Keller Maria, Villringer Arno, Stumvoll Michael, Tönjes Anke, Kovacs Peter, Böttcher Yvonne
Abstract excerpt
BACKGROUND: The human Aldoketoreductase 1B10 gene (AKR1B10) encodes one of the enzymes belonging to the family of aldoketoreductases and may be involved in detoxification of nutrients during digestion. Further, AKR1B10 mRNA (messenger ribonucleic acid) expression was diminished in brain regions potentially involved in the regulation of eating behavior in rats which are more sensitive to cocaine and alcohol. We...
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