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Article

Correlation between mutational status and survival and second cancer risk assessment in patients with gastrointestinal stromal tumors: a population-based study.

World journal of surgical oncology - 13 Feb 2015

Rubió-Casadevall Jordi, Borràs Joan Lluis, Carmona-García Maria Carme, Ameijide Alberto, Gonzalez-Vidal Allan, Ortiz Maria Rosa, Bosch Ramon, Riu Francesc, Parada David, Martí Esther, Miró Josefina, Sirvent Juan Jose, Galceran Jaume, Marcos-Gragera Rafael

Abstract excerpt

BACKGROUND: Gastrointestinal stromal tumors are sarcomas of the digestive tract characterized by mutations mainly located in the c-KIT or in the platelet-derived growth factor receptor (PDGFR)-alpha genes. Mutations in the BRAF gene have also been described. Our purpose is to define the distribution of c-KIT, PDGFR and BRAF mutations in a population-based cohort of gastrointestinal stromal tumors (GIST) patients...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins B-raf

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Source

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Identifiers

PMID: 25885906
DOI: 10.1186/s12957-015-0474-0
PMCID: PMC4336765

Genes

KIT
BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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