Article
Screening of exon 11 of BRCA1 gene using the high resolution melting approach for diagnosis in Moroccan breast cancer patients.
BMC cancer - 25 Feb 2015
El Khachibi Meryam, Diakite Brehima, Hamzi Khalil, Badou Abdallah, Senhaji Mohamed Amine, Bakhchane Amina, Jouhadi Hassan, Barakat Abdelhamid, Benider Abdellatif, Nadifi Sellama
Abstract excerpt
BACKGROUND: Identification of specific mutations in cancer patients may lead to the discovery of genes, which can affect susceptibility and/or prognosis. It has previously been reported that mutations in BRCA1 and BRCA2 genes are linked to breast cancer. Here, we evaluated the use of the High Resolution Melting (HRM) approach to screen for mutations in exon 11 of BRCA1 gene in Moroccan patients. METHODS: HRM...
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