Article
ReMo-SNPs: a new software tool for identification of polymorphisms in regions and motifs genome-wide.
Genetics research - 17 Apr 2015
Graae Lisette, Paddock Silvia, Belin Andrea Carmine
Abstract excerpt
Studies of complex genetic diseases have revealed many risk factors of small effect, but the combined amount of heritability explained is still low. Genome-wide association studies are often underpowered to identify true effects because of the very large number of parallel tests. There is, therefore, a great need to generate data sets that are enriched for those markers that have an increased a priori chance of...
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