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Article

Leukocyte adhesion deficiency-I with a novel intronic mutation presenting with pyoderma gangrenosum- like lesions.

Journal of clinical immunology - 1 May 2015

Madkaikar Manisha, Italia Khushnooma, Gupta Maya, Desai Mukesh, Aggarwal Amita, Singh Surjit, Suri Deepti, Mishra Anju, Chavan Sushant, Ghosh Kanjaksha, Sarangal Rishu, Dogra Sunil

Abstract excerpt

Pyoderma gangrenosum (PG) is an uncommon noninfectious neutrophilic dermatosis characterized by recurrent, sterile, necrotic skin ulcers. It is commonly associated with underlying systemic disease like inflammatory bowel disease, rheumatoid arthritis and hematological malignancies. Pathogenesis of PG remains unclear though aberrant immune responses have been implicated. The diagnosis of PG is of exclusion and...

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Identifiers

PMID: 25876705
DOI: 10.1007/s10875-015-0155-3

Genes

ITGB2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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