Article
What can inherited immunodeficiencies reveal about pyoderma gangrenosum?
Experimental dermatology - 1 Jan 2024
Oprea Yasmine, Kody Shannon, Shakshouk Hadir, Greiling Teri M, Anstey Karen M, Ortega-Loayza Alex G
Abstract excerpt
Pyoderma gangrenosum (PG) is a rare ulcerative neutrophilic dermatosis that is occasionally associated with primary immunodeficiency. Though contributions from dysregulation of the innate immune system, neutrophil dysfunction and genetic predisposition have been postulated, the precise pathogenesis of PG has not yet been elucidated. This article reviews reported cases of coexisting PG and primary immunodeficiency...
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