Article
Pyoderma Gangrenosum: An Update on Pathophysiology, Diagnosis and Treatment.
American journal of clinical dermatology - 1 Jun 2017
Alavi Afsaneh, French Lars E, Davis Mark D, Brassard Alain, Kirsner Robert S
Abstract excerpt
Pyoderma gangrenosum (PG) is a rare inflammatory neutrophilic disorder with prototypical clinical presentations. Its pathophysiology is complex and not fully explained. Recent information regarding the genetic basis of PG and the role of auto-inflammation provides a better understanding of the disease and new therapeutic targets. PG equally affects patients of both sexes and of any age. Uncontrolled cutaneous...
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