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Article

Human Mutated MYOT and CRYAB Genes Cause a Myopathic Phenotype in Zebrafish.

International journal of molecular sciences - 14 Jul 2023

Cannone Elena, Guglielmi Valeria, Marchetto Giulia, Tobia Chiara, Gnutti Barbara, Cisterna Barbara, Tonin Paola, Barbon Alessandro, Vattemi Gaetano, Schiavone Marco

Abstract excerpt

Myofibrillar myopathies (MFMs) are a group of hereditary neuromuscular disorders sharing common histological features, such as myofibrillar derangement, Z-disk disintegration, and the accumulation of degradation products into protein aggregates. They are caused by mutations in several genes that encode either structural proteins or molecular chaperones. Nevertheless, the mechanisms by which mutated genes result...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 37511242
DOI: 10.3390/ijms241411483
PMCID: PMC10380269

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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