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Article

Linking a compound-heterozygous Parkin mutant (Q311R and A371T) to Parkinson's disease by using proteomic and molecular approaches.

Neurochemistry international - 1 Jan 2000

Ozgul Sinem, Kasap Murat, Akpinar Gurler, Kanli Aylin, Güzel Nil, Karaosmanoglu Kübra, Baykal Ahmet Tarik, Iseri Pervin

Abstract excerpt

Parkin is an E3-protein ubiquitin ligase, which plays an important role as a scavenger in cell metabolism. Since the discovery of the link between Parkin and Parkinson's disease, Parkin was placed in the center of Parkinson's disease research. Previously, we isolated a mutant form of the Parkin p...

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Source

Identifiers

PMID: 25865804
DOI: 10.1016/j.neuint.2015.03.007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25865804-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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